Reference values of carotid-femoral pulse wave velocity (PWV1), the gold standard measure of arterial stiffness, and local carotid2 and femoral3 arterial stiffness, derived from the distensibility coefficient (DC), have been established. The use of different devices and methods, however, still hampers the widespread clinical use of these reference values. With this calculator, we provide a web-based application that allows easy assessment – for different methodological approaches – of a given measured value of arterial stiffness, with the application providing the percentile reference value associated with that specific value. Individuals without CVD and established cardiovascular risk factors from the respective studies constituted a healthy subpopulation and were used to establish equations for percentiles of PWV and sex-specific percentiles of carotid and femoral DC across age.

Click here to view the PWV-calculator/converter

1: Determinants of pulse wave velocity in healthy people and in the presence of cardiovascular risk factors: ‘establishing normal and reference values’. Reference Values for Arterial Stiffness’ Collaboration. Eur Heart J. 2010 Oct;31(19):2338-50. doi: 10.1093/eurheartj/ehq165

2: Reference values for local arterial stiffness. Part A: carotid artery. Engelen L, Bossuyt J, Ferreira I, van Bortel LM, Reesink KD, Segers P, Stehouwer CD, Laurent S, Boutouyrie P; Reference Values for Arterial Measurements Collaboration.. J Hypertens. 2015 Oct;33(10):1981-96. doi: 10.1097/HJH.0000000000000654.

3: Reference values for local arterial stiffness. Part B: femoral artery. Bossuyt J, Engelen L, Ferreira I, Stehouwer CD, Boutouyrie P, Laurent S, Segers P, Reesink K, Van Bortel LM; Reference Values for Arterial Measurements Collaboration. J Hypertens. 2015 Oct;33(10):1997-2009. doi: 10.1097/HJH.0000000000000655

The tool has been developed by

Francisco Londoño
Luc Van Bortel
Patrick Segers

Reference (abstract only): 4D.01: A SIMPLE CALCULATOR FOR THE ASSESSMENT OF MEASUREMENTS OF CAROTID-FEMORAL PULSE WAVE VELOCITY AND LOCAL ARTERIAL STIFFNESS RELATIVE TO THE REFERENCE VALUES DATABASE. Londono F, Bossuyt J, Engelen L, Stehouwer C, Ferreira I, Laurent S, Boutouyrie P, Segers P, Van Bortel L.  J Hypertens. 2015 Jun;33 Suppl 1:e60-e. doi: 10.1097/01.hjh.0000467505.60342.95.